Product	Description	Quantity	Form	Manufacturer	Price	Order
Tempalgin	0.5 mg	10	Tablets	Sopharma	$ 6.00

Tempalgin

Note: If this brand is out of stock, another brand will be send to you. Active ingredient and concentration will be the same.

Indications:
Mild to moderate pain of variable origin: headache; migrene; toothache; neuralgia; neuritis; plexitis; lumbalgia; myalgia and myositis; trauma; postsurgery interventions and dental procedures; dysmenorrhoea; burning; premedication in the dental practice.

Dosage and administration:
In adults, Tempalgin is used orally in dose of 1 - 2 tablets 3 - 4 times daily. In children over 10 years, the drug is administered in dose of 1 tablet 2 - 3 times daily. The treatment course duration should not exceed 5 to 7 days.

Contraindications:
Hypersensitivity to tempidon, metamizole and other pyrazolone drugs; acute hepatic porphyria and inborn deficiency of glucose-6-phosphate dehydrogenase; aplastic anemia, leucopenia and agranulocytosis; severe kidney and liver diseases; pregnancy; children younger than of 10 years.

Special warnings and precautions:
The drug is used cautiously in patients suffering from liver or kidney diseases. After more prolonged treatment with Tempalgin regular checks of blood count are necessary. In patients suffering from bronchial asthma, pollinosis, Quincke's edema, chronic airway infections or showing hypersensitivity to analgesic and nonsteroidal anti-inflammatory agents, as well as to other drugs or foods, there is a risk of allergic reactions and asthmatic attacks. During lactation the drug should be avoided, because both active ingredients are eliminated in the breast milk. Tempidon decreases the attention concentration and slows the reflexes. Because of this it should be used cautiously in car drivers and in people working with machines.

Drug interactions:
Because of the inhibition of hepatic enzyme systems metabolising drugs, Metamizole effect is potentiated by tricyclic antidepressants (psychophorin, amitriptyline), oral contraceptive agents, and allopurinol. Due to this its biotransformation is slower, and the toxicity is greater. Barbiturates and phenylbutazone are liver enzyme inductors, and they decrease the strength and duration of the metamizole pharmacodynamic effect. Metamizole lowers the plasma cyclosporin levels. Chloramphenicol increases the myelotoxic action of metamizole (additive effect). Alcohol augments the action of both components. Tempidon potentiates the activity of the hypnotic agents, general anesthetics, and narcotic and nonnarcotic analgesics.

Adverse reactions:
Itching, skin rash, urticaria, Stevens-Johnson's syndrome, Layell's syndrome, angioedema, vasomotor disturbances; asthmatic attack, allergic shock; nausea, vomiting, abdominal pain and discomfort, ulcers and bleeding in rare cases. In susceptible patients, agranulocytosis, leucopenia, aplastic anemia, retention of water and electrolytes are possible.